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Study of 168 participants: 85 supplemented with B vitamins had a mean rate of brain atrophy after 2 years of .76% vs. 1.08% for the control group.
In the treatment group homocysteine levels greater than 13 had results more dramatic, rate of atrophy was 53% lower.
Low dose supplementation was used: 800 mcg folic acid, 500 mcg cyanocobalamin & 20 mg of pyridoxine HCL.
B12-
Brain Atrophy
Study